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Tramadol is a narcotic-like pain reliever. Tramadol is used to treat moderate to severe pain.

Tramadol possesses weak agonist actions at the µ-opioid receptor, releases serotonin, and inhibits the reuptake of norepinephrine. Tramadol is a synthetic stripped-down piperidine-analog of the phenantherane alkaloid codeine and, as such, is an opioid and also a prodrug. The opioid agonistic effect of Tramadol are almost exclusively mediated by the substance’s action at the µ-opioid receptor.


Important information about Tramadol


You should not take Tramadol if you have ever been addicted to drugs or alcohol.

Seizures (convulsions) have occurred in some people taking Tramadol. You may be more likely to have a seizure while taking tramadol if you have a history of seizures or head injury, a metabolic disorder, or if you are taking certain medicines such as antidepressants, muscle relaxers, or medicine for nausea and vomiting.


Take Tramadol exactly as it was prescribed for you. Do not take it in larger doses or for longer than recommended by your doctor. Do not take more than 300 milligrams of Tramadol in one day.


Do not crush the Tramadol tablet. This medicine is for oral (by mouth) use only. Powder from a crushed tablet should not be inhaled or diluted with liquid and injected into the body. Using this medicine by inhalation or injection can cause life-threatening side effects, overdose, or death.


Tramadol Side Effects


The most commonly reported adverse drug reactions are

-nausea,

-vomiting,

-sweating

-constipation


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