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Soma is a muscle relaxer that works by blocking pain sensations between the nerves and the brain. Soma is used together with rest and physical therapy to treat injuries and other painful musculoskeletal conditions. The drug is is a colorless, crystalline powder, having a mild characteristic odor and a bitter taste. It is slightly soluble in water and freely soluble in alcohol, chloroform and acetone. It had been developed by Dr. Frank M. Berger at Wallace Laboratories and had been named carisoprodol (trade name Soma). Soma has a rapid, 30 minute onset of action, with the aforementioned effects lasting for approximately 2?6 hours. It is metabolized in the liver via the cytochrome P450 oxidase isozyme CYP2C19, excreted by the kidneys and has an approximate 8 hour half-life.


Soma Side Effects


The usual dose of 350 mg is unlikely to engender prominent side effects other than somnolence. The medication is well tolerated and without adverse effects in the majority of patients for which it is indicated. In some patients however, and/or early in therapy, Soma can have the full spectrum of sedative side effects and can impair the patient’s ability to operate a firearm, motorcycle, and other machinery of various types especially when taken with medications containing alcohol, in which case an alternative medication would be considered. The intensity of the side effects of Soma tends to lessen as therapy continues, as is the case with many other drugs.


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